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N. Mimura

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Open access Aug 2026

Stroma-Dominant Colorectal Cancer Harbors CAF-Rich Spatial Architecture and EMT-Associated Cancer Cell Plasticity Detectable After Dissemination

Stroma-dominant CRC is characterized as a spatially organized ecosystem in which a CAF-rich compartment is associated with stress-adapted cancer cell programs, and its poor prognosis may involve not only stromal abundance but also a morphology-associated cancer cell state detectable after dissemination.

S. Kitagawa, N. Mimura, Hironobu Kambara et al. · 0 citations

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