Author

N. Matange

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Review Open access Oct 2026

Meeting gene expression demand during evolution of antibiotic resistance.

Regulated gene expression in bacteria accommodates demands imposed by different environments. In addition to ensuring the production of required metabolic and structural components, gene regulation protects bacteria against the adverse effects of misexpression. Upon encountering a novel environment, such as sustained e...

Rhea Vinchhi, N. Matange · Genetics · 0 citations

Open access Oct 2026

Divergent genotype-phenotype maps determine the capacity for adaptation to antibiotics among Enterobacteria

It is discovered that the mere presence of effector genes of resistance, as well as conserved gene regulatory architecture, do not necessarily translate to similar evolvabilities during antibiotic challenge, and the importance of understanding pathogen-specific genotype-phenotype maps of drug resistance to better predi...

Rhea Vinchhi, Ashani Joshi, Seona Paranjape et al. · bioRxiv · 0 citations