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In patients with heart failure and advanced chronic kidney disease, CCBs use was associated with improved survival, supporting their potential role as a safe adjunctive therapy for blood pressure control in this high-risk population.
In asymptomatic adults without structural heart disease, the clinical determinants and long-term prognostic trajectories of ectopy exhibit a profound chamber-specific divergence and stands out as a powerful, independent marker of intrinsic electrical vulnerability and long-term cardiovascular risk.
Frailty fundamentally attenuates risk in HF, while multimorbidity stratifies prognosis only when physiological reserve is preserved, while multimorbidity stratifies prognosis only when physiological reserve is preserved.
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