Sep 2026
A nucleolar assembly module integrates an ancestral isoaspartylase to safeguard ribosome biogenesis
A. G. Geiger, Sébastien Favre, Oscar Vadas et al.
· bioRxiv · 0 citations
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Open access
Aug 2026
Universally conserved isoasparylation sustains ribosome biogenesis and function
All living beings use ribosomes to synthesize proteins from α-amino acids. Inherited from our common ancestor, a few universally conserved ribosome biogenesis steps, introducing essential ribosomal RNA modifications, have survived to our days. However, it was unknown whether similar primordial core mechanisms could als...
Bruno Bonnettaz, Anna Smirnova, Marlène Vayssières et al.
· bioRxiv · 0 citations