Nanoparticle- and MSC-reinforced thermosensitive chitosan hydrogel for controlled antibiotic release and bone regeneration.
Critical-sized bone defects pose major challenges in orthopedic tissue engineering due to their limited self-repair capacity and high risk of infection. To address these issues, we developed an injectable, thermoresponsive, and biodegradable chitosan (CS)-based hydrogel reinforced with mesoporous zinc-silicate (mZS) na...