AI Networking Cookbook: Practical recipes for AI-assisted network automation and development
We have 4 of 331 papers
We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.
Not the right person? Other researchers publish under this name.
High-affinity single domain antibodies, (also known as VHHs or Nanobodies) that allo- or orthosterically modulate ligand binding of Siglec-1 are identified and may serve as broad-spectrum pathogen blocking agents.
A capsid-targeting biological composed of a single-domain Llama VHH that binds CA, fused to human IgG1 Fc to activate TRIM21-mediated degradation results in inhibition of viral replication through TRIM21-mediated proteasome degradation of the HIV-1 capsid, establishing capsid-directed biologicals as therapeutic strateg...
Newly developed single-domain antibodies against Siglec-1 are used against Siglec-1 as a candidate inhibitor to limit HIV-1 transmission and support the development of host-directed nanobody-based strategies to reduce HIV-1 spread.
The results demonstrate the broad neutralization potential of anti-capsid biologics with a high barrier to resistance, making capsid-targeting inhibitors important for novel antiretroviral drug strategies worldwide.
We use cookies to run the site and, with your consent, for analytics and to show ads. See our Cookie Policy.