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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

N. Jahanshad

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5 papers indexed here

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Open access Aug 2026

Diagnostic classifications based on cognitive, CSF, and PET biomarkers across ADNI cohorts: cross-sectional and longitudinal variability

Alzheimer’s disease and related neurodegenerative disorders exhibit marked clinicobiological heterogeneity, posing challenges for accurate diagnosis, prognosis, and therapeutic development. Using data from multiple cohorts of the Alzheimer’s Disease Neuroimaging Initiative (ADNI), we conducted comprehensive cross-sec...

Maryam Fotouhi, H. Chui, J. Choupan et al. · 0 citations
Open access Sep 2026

Tissue- and compartment-resolved brain age reveals vascular-metabolic and neurodegenerative aging

Abstract Brain aging reflects heterogeneous vascular-metabolic and neurodegenerative processes, yet brain age is often reduced to a gray matter (GM)-dominant estimate. Emerging evidence suggests that subtle “dirty-appearing” T2-FLAIR abnormalities may mark diffuse white matter (WM) vulnerability that precedes or extend...

Hosung Kim, Cong Zang, Jin-Soo Lee et al. · 0 citations
Open access Aug 2026

Assessing molecular, cellular and transcriptomic bases of laminar perfusion and cytoarchitecture coupling in the human cortex

Understanding how cellular architecture shapes cortical function requires mesoscopic approaches that resolve structure-function relationships in vivo. Here we introduce the cerebral blood flow (CBF) – cell-body staining intensity (CSI) similarity index (CCSI), a quantitative measure of laminar perfusion-cytoarchitectur...

Fan-Hua Guo, Chen-Yang Zhao, Ravi R. Bhatt et al. · 0 citations
Nov 2025

Assessing molecular, cellular and transcriptomic bases of laminar perfusion and cytoarchitecture coupling in the human cortex

Understanding how cellular architecture organizes cortical function requires mesoscopic approaches that resolve structure-function coupling in vivo. Here we introduce cerebral blood flow (CBF) and cell-body staining intensity (CSI) similarity index (CCSI), a localized similarity index between the CBF estimates from ult...

Fan-Hua Guo, Chen-Yang Zhao, Ravi R. Bhatt et al. · 0 citations
Open access Sep 2026

Regional choroid plexus calcifications and their associations with aging, brain structure, and disease

The choroid plexus (CP) maintains brain homeostasis through cerebrospinal fluid production and formation of the blood-cerebrospinal fluid barrier, and its dysfunction has been linked with aging and neurological disease. CP dysfunction may involve both enlargement and calcific tissue change, which may reflect distinct p...

Iyad Ba Gari, Alyssa H. Zhu, Ravi R. Bhatt et al. · 0 citations

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