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Author

N. Galić

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Open access Oct 2026

Functional evaluation of loratadine–cyclodextrin complexes: comprehensive solid-state characterisation, biopharmaceutical assessment and stability profiling

Loratadine (LOR) is a poorly water-soluble antihistaminic drug whose solubility can be significantly enhanced in water and biorelevant media through inclusion complexation with β-cyclodextrins (β-CDs), as we have shown previously. In this work, we investigated the biopharmaceutical properties and chemical stability of...

M. Pocrnić, Marek J. Potrzebowski, Mario Jug et al. · 0 citations
Oct 2026

Comprehensive analysis of peptide pharmaceutical: Development of three orthogonal chromatographic methods and characterization of bivalirudin degradation products by high-resolution mass spectrometry.

Bivalirudin is a synthetic oligopeptide used as an anticoagulant for the treatment of acute coronary syndromes and for the prevention of thrombosis in patients undergoing percutaneous coronary intervention. As peptides are complex molecules that may exhibit inherently complex impurity profiles, three orthogonal ultra-p...

A. Vukoja, Elena Pavić, Sanja Galović et al. · 0 citations

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