Open access
Sep 2026
OVX033 nucleocapsid vaccine induces cross-reactive T cells and boosts memory in SARS-CoV-2-primed non-human primates
SARS-CoV-2 Spike protein evolution compromises sustained efficacy of existing vaccines based on neutralizing antibodies. Here we show that OVX033, a nucleocapsid (NCAP)-based vaccine candidate engineered with the self-assembling oligoDOM™ domain, induces robust cellular immunity in two preclinical models. In hamste...
R. Marlin, C. Primard, Anne-Sophie Gallouët et al.
· Communications Biology · 0 citations