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Preprint Sep 2026

Towards more plausible point-identifying assumptions in two-sample Mendelian randomization

Two-sample Mendelian randomization (MR) is a widely applied methodology in epidemiology. In two-sample MR, summary data (typically, regression coefficients and standard errors) quantifying the association between multiple genetic variants and the exposure and the outcome are used in an instrumental variable framework a...

F. Hartwig, N. Davies, George Davey Smith · 2 citations

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