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N. Chatterjee

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Open access Sep 2026

Population-scale plasma proteomics reveals pre-diagnostic biomarkers and shared pathways of cancer risk across 25 cancers

Abstract The causes of most cancers remain unknown because the biological pathways underlying cancer development are poorly understood. Large-scale plasma proteomics offers a powerful strategy to uncover these pathways, identify biomarkers for cancer early detection, and discover novel therapeutic targets but has rarel...

J. Yarmolinsky, V. Viallon, V. Burk et al. · 0 citations
Open access Aug 2026

TLS-Tractor: A transfer learning framework for incorporating summary-statistics into local ancestry-aware GWAS in admixed populations

TLS-Tractor is introduced, a transfer-learning method that uses the generalized method of moments to integrate external GWAS summary statistics with internal individual-level data for local ancestry-aware association analysis and shows that local ancestry adjustment can improve calibration, localization, and interpreta...

Wenxuan Lu, Ruzhang Zhao, N. Chatterjee · 0 citations

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