Author

N. Chambwe

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Oct 2026

Abstract C126: Integrated whole genome and transcriptome analyses reveal ancestry-associated molecular features of breast cancer

Women of African ancestry experience disproportionately aggressive breast cancer (BC) and poorer survival yet remain substantially underrepresented in cancer genomic studies. Consequently, the contribution of inherited genetic ancestry to breast tumor biology remains poorly understood. To address this gap, we lev...

Rachel Martini, William Hooper, Timothy R. Chu et al. · Cancer Epidemiology, Biomark... · 0 citations

Oct 2026

Abstract C130: A genetic ancestry-informed single-cell atlas of the endometrial cancer tumor microenvironment reveals ancestry-associated immune features with potential clinical implications

Genetic ancestry-associated differences in the tumor immune profile have been identified in multiple cancer types but remain largely uncharacterized in endometrial cancer (EC). These tumor microenvironment (TME) features, such as cytotoxic immune cell infiltration and functionality, influence disease progression, tum...

Emma Saart, K. Lundy-Perez, N. Chambwe · Cancer Epidemiology, Biomark... · 0 citations

Review Open access Aug 2026

Rigorous Female Breast Cancer Phenotyping Using the All of Us Research Program

Objectives Accurate phenotyping of cases and controls is essential for studying biological and environmental contributors to disease in large biobanks. We aimed to develop a flexible, customizable, and reproducible electronic health record (EHR)-based phenotyping framework for identifying disease cases and generating m...

Y. Qi, K. Lundy-Perez, D. Gee et al. · medRxiv · 0 citations