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N. Alshammari

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Open access Sep 2026

Engineering a sulfadoxine-functionalized NH2–UiO-66(Zr) metal–organic framework via post-synthetic modification for dual-mode spectrophotometric and fluorometric detection of Cd2+

The sustainable development of a metal–organic framework (MOF) composite was performed for the sensing of hazardous cadmium(ii) contamination in water, providing a successful MOF material through post-synthetic modification involving the integration of SDX and GA (SDX–GA@UiO-66). Physicochemical characterization was pe...

A. A. H. Bukhari, Nadia H. Elsayed, N. Alshammari et al. · 0 citations
Open access Aug 2026

Mechanistic insights into antioxidant and antibacterial effects of indole-pyrazole-carbohydrazide hybrids through density functional theory, docking, and molecular dynamics studies

A new series of indole-pyrazole-carbohydrazide derivatives ( IH-1-IH-5 ) was synthesized through acid-catalyzed condensation of 1H-indole-5-carbaldehyde with substituted pyrazole-5-carbohydrazides, aiming to develop multifunctional antioxidants and antibacterials. In2,2′-diphenyl-1-picrylhydrazyl (DPPH) assays, ele...

Shorog M. Alotaiby, Samar J. Almehmadi, Nuha M. Halawani et al. · 0 citations
Open access Aug 2026

Synthesis, modelling, biological activity of new thiophene hybridized with pyrazole, and/or pyridine analogues as potential DNA gyrase and topoisomerase IV inhibitors

The study displayed the synthesis of two series of thiophene-pyrazole hybrids, 7a-c and thiophene-pyridine hybrids 9a-c, via reacting arylhydrazone with halogenated reagents and nucleophilic addition of cyanoacetamide to the arylidene-malononitrile, respectively, and the chemical structure was elucidated using relia...

Abdulrahman S. Alharbi, Shadiah Albalawi, Asmaa L Alanzy et al. · 0 citations

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