Age-associated hematopoietic skewing results in an increase in the neutrophil-to-lymphocyte ratio, which serves as a strong predictor of all-cause mortality in older adults, although its causes are incompletely understood. Here we show that cytotoxic CD4+ T lymphocytes accumulate in the bone marrow of mice during aging...
E. Gabandé-Rodríguez, G. Soto-Heredero, Elisa Carrasco et al.· Nature Aging· 0 citations
It is proposed that the convergence of biology and artificial intelligence and the continued innovation in deep learning-based cell segmentation will accelerate method development, standardization, and deployment in both basic biological research and clinical applications.
Isabelle A. Rathbun, N. Banskota, E. Lehrmann et al.· Nucleic Acids Research· 0 citations
It is proposed that the age-associated reduction in LANCL1-AS1 contributes to impaired mitochondrial function and reduced myogenic capacity in aging skeletal muscle.
Jen-Hao Yang, Elizabeth K. Izydore, K. Mazan-Mamczarz et al.· bioRxiv· 0 citations
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