Author

Muriel Elhai

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Open access Aug 2026

Radiomic analysis of high-resolution computed tomography predicts interstitial lung disease progression and mortality in systemic sclerosis

Abstract Objective The automated assessment of chest high-resolution CT (HRCT) scans allows the objective quantification of interstitial lung disease (ILD)–related features. Here, we explored the ability of HRCT-derived radiomic features to predict all-cause mortality and ILD progression in SSc-ILD patients. Methods We...

Maria Iacovantuono, N. Landini, Lisa Jungblut et al. · Rheumatology · 0 citations

Review Open access Sep 2026

Conceptual framework for the definition of disease modification in systemic sclerosis and potential implications for drug development and clinical study design.

Systemic sclerosis (SSc) is a multifaceted systemic autoimmune disease, characterised by the interplay of vascular alterations, immune dysregulation, and fibrosis. The molecular changes and the clinical presentation of SSc are highly heterogeneous and vary considerably between individual patients. This heterogeneity ha...

Jörg H. W. Distler, S. Assassi, A. Gabrielli et al. · Annals of the Rheumatic Dise... · 0 citations