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Mukul Shyam

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Review Open access Aug 2026

Sesamum indicum-derived valdiate as a novel neuroprotective agent targeting PDE10A2 and SIRT1 in Huntington’s disease

Background Huntington’s disease is prevalent globally, with approximately 4.88 cases per 100,000 people, based on a systematic review and meta-analysis of 33 studies published between 2010 and 2022. Despite its significant prevalence, no proper treatment is available that directly addresses Huntington’s disease. The ex...

Mukul Shyam, M. D. Wafi Ismail, Deepak Sharma et al. · 0 citations

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