Serum Metabolomics and Multiomics Validation Reveal Zishangan Granule-Induced P53-Bax/Casp3 Signaling in NSCLC.
Nonsmall cell lung cancer (NSCLC) remains a major cause of cancer mortality, underscoring the need for multitarget therapeutic candidates with defined mechanisms. This study investigated the anti-NSCLC activity of Zishangan Granule (ZSG), a four-herb formulation, using serum metabolomics, network pharmacology, molecula...