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Author

Muhammad Tahir Naseem

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Sep 2026

Chronic labetalol exposure induced dose-dependent testicular toxicity via disruptingt HPG-axis, spermatogenesis and steroidogenic pathways: A biochemical, molecular and histopathological evidence.

Labetalol (LBL) is a combined-alpha and non-selective β-adrenergic receptor antagonist commonly prescribed for high blood pressure patients. However, LBL intoxication showed severe toxicity including testicular impairments. This experimental study aimed to elucidate the dose-responsive reproductive perturbations of LBL...

Salim Jamil, F. M. Alzahrani, Khalaf F. Alsharif et al. · 0 citations
Review Sep 2026

Beyond copy number: circulating cell-free mitochondrial DNA Fragmentomics and structural states in liquid biopsy.

A laboratory-medicine framework in which cf-mtDNA is considered a multidimensional analyte rather than a single abundance variable is developed, and the central implication is that the next phase of cf-mtDNA diagnostics will depend less on measuring more DNA than on measuring the correct molecular fraction with traceab...

Muhammad Tahir Naseem, W. Zaman, Aziz Ullah · 0 citations

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