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Muhammad Muddasar Saeed

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Open access Sep 2026

Bufalin Targets CENPA-modulated Glycolysis via PI3K/AKT in Hepatocellular Carcinoma: A Bioinformatics, In Vitro and Preliminary In Vivo Evidence.

BACKGROUND Hepatocellular carcinoma (HCC) remains a substantial therapeutic challenge because of its high recurrence rate and resistance to conventional therapies, necessitating the exploration of novel approaches. A crucial aspect of cancer metabolism is the Warburg effect, which promotes tumor progression by increasi...

Muhammad Muddasar Saeed, Tian-Fu Wei, Muhammad K. Iqbal et al. · 0 citations
Review Open access Sep 2026

Artificial intelligence in mental health: A narrative review of applications, benefits, and ethical challenges

The review found that AI tools—for example, selfreferral chatbots that reduced waiting times and increased treatment uptake—provide expanded 24/7 access, improved clinical efficiency, and potential for individualised personalisation, while Predictive models showed promise for treatment selection and risk stratification...

Shizal Nawaz, Laiba Nawaz, Hasnain Ali et al. · 0 citations
Jul 2026

Repurposing simeprevir uncovers a druggable KPNB1-p65-BCL2 survival axis in cancer.

This study elucidates a therapeutically targetable KPNB1-p65-Bcl-2 survival axis in multiple cancers and establishes a foundation for developing next-generation KPNB1 inhibitors.

Cong Li, Qiaohua Yan, Muhammad Muddasar Saeed et al. · 0 citations

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