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Mudit Sharma

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#diffusion models Open access Sep 2026

AF-RECAL: Multi-Modal Structural Recalibration of AlphaFold 3 Hallucinations in Intrinsically Disordered Human Disease Targets

AlphaFold 3 (AF3) has transformed structural bioinformatics through generative diffusion modeling of biomolecular assemblies. However, intrinsically disordered regions (IDRs)—which comprise over 30% of the human proteome and mediate essential cell signaling, oncogenesis, and phase separation—violate the classic thermod...

Mudit Sharma · 0 citations

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