Antiretroviral therapy (ART) suppressed HIV replication and permitted partial restoration of CD4+ T cell immunity, yet the magnitude and tempo of immune recovery vary widely among treatment-naïve patients. Incomplete CD4 reconstitution sustained vulnerability to opportunistic infections, immune activation, and nonAIDS...
Mpora Kakwanzi Evelyn· IDOSR Journal of Applied Sci...· 0 citations
Emerging evidence indicates that the prostate, liver, and immune system are linked through common molecular and cellular pathways that influence disease development beyond organ-specific boundaries. Traditionally, benign prostatic hyperplasia (BPH) has been viewed as an isolated urological condition of aging males, whi...
Mpora Kakwanzi Evelyn· IDOSR Journal of Applied Sci...· 0 citations
Cytochrome P450 enzymes (CYP450), nuclear factor erythroid 2-related factor 2 (Nrf2), and nuclear factor-κB (NF-κB) have long been studied individually in toxicology, oxidative stress, and immune activation. Emerging evidence now positions these molecules as central, interacting regulators of multisystem chronic diseas...
Mpora Kakwanzi Evelyn· IDOSR Journal of Applied Sci...· 0 citations
Type 2 diabetes mellitus (T2DM) is a leading cause of cardiovascular and renal complications worldwide, contributing significantly to morbidity and mortality. The advent of sodium-glucose cotransporter 2 (SGLT2) inhibitors represented a novel therapeutic approach, offering not only glycemic control but also substantial...
Mpora Kakwanzi Evelyn· Idosr Journal of Science and...· 0 citations
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