T-cell senescence and immunosenescence in chronic oral mucosal inflammatory diseases: mechanisms and therapeutic implications
Abstract Background The oral mucosa is a dynamic barrier. T‑cell dysregulation contributes to chronic oral mucosal inflammatory diseases, but the role of age‑related immune remodeling remains unclear.. Method We performed a narrative review of PubMed/Medline (1972–2026) on T‑cell subsets, immunosenescence, exhaustion,...