Open access
Jul 2026
Chronic CBD treatment differentially modulates neurobehavioral outcomes and endocannabinoid signaling in an aged HIV-1 Tat transgenic mouse model
It is demonstrated that chronic CBD intervention interacts with the eCB system of aged mice in a region-specific manner and underscores the critical importance of considering age, sex, and treatment duration when evaluating cannabinoid-based therapies for the management of neuroHIV.
Barkha J. Yadav-Samudrala, Morgan L Johnson, Ashima Ale et al.
· PLoS ONE · 0 citations