The rapid rise in drug-resistant infectious diseases urgently demands new therapeutic strategies, particularly against fungi. Antimicrobial peptides (AMPs) are key effectors of innate immunity in all organisms, killing various microorganisms. Despite their potential, few AMPs effectively target pathogens without harm...
Daniel Ben Hur, N. A. Wani, Elad Stolovicki et al.· Journal of Medicinal Chemist...· 0 citations
Rising bacterial antimicrobial resistance is one of the major threats and challenges of current global healthcare. Estimating for approximately 1,27 million deaths a year and US$ 66 billion per year in health economic burden.
One of the key tools in tackling antimicrobial resistance is efficient and accurate dia...
Adrianna Olejniczak, S. Bajer-Borstyn, Monika Kluzek et al.· Clinical Chemistry· 0 citations
Healthy articular cartilage exhibits a very low coefficient of friction (CoF ≈ 0.002-0.02) due to hydration lubrication at the slip plane, involving phospholipids bound to macromolecules in the cartilage matrix. Hydrogels that mimic this hydrated phosphorylcholine layer could replicate cartilage lubrication for biomedi...