Mónica L. García-Gómez

When do hybrid models help? Combining mechanistic modelling and machine learning to predict gene regulatory network dynamics

Gene regulatory networks (GRNs) are a crucial link between genotype and phenotype, allowing organisms to respond to their environment by altering gene expression over time. Models can help us understand the underlying logic of these GRNs; in particular, ordinary differential equation (ODE) models are suitable for this,...