Recombinant Spinach Ribosome-Inactivating Protein Induces Cytotoxicity and Alters Gene Expression Associated with PTEN/AKT/mTOR Signaling, Apoptosis, and Stemness in HT29 cells.
Colorectal cancer (CRC) remains a major therapeutic challenge, highlighting the need for novel anticancer strategies. These challenges have increased interest in bioactive natural molecules with anticancer potential. In this study, we investigated the antitumor activity of a recombinant spinach (Spinacia oleracea) type...