Psoriasis is a chronic, immune-mediated inflammatory skin disorder characterized by dysregulated keratinocyte proliferation, aberrant immune activation, and impaired skin barrier function. Despite the availability of conventional topical, systemic, and biologic therapies, their long-term efficacy is often limited by...
Devesh Kumar, Jaspreet Kaur, Ankit Awasthi et al.· Journal of Materials Science...· 0 citations
The present study describes the development and validation of a simple, rapid, and reliable RP-HPLC method for the simultaneous estimation of acyclovir and doxepin hydrochloride in bulk and topical cream formulation using an Analytical Quality by Design (AQbD) approach. The combination of acyclovir, an antiviral agent,...
The incorporation of cubosomes into a thermosensitive in-situ gel and surface modification with chitosan significantly improved formulation stability and enabled controlled drug release, highlighting the potential of CHT-AGN-CB-gel as a promising localized delivery platform for cervical cancer management, offering sust...
Muskaan Sharma, Devesh Kumar, Mohit Kumar et al.· International Journal of Bio...· 0 citations
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