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Author

Mohammed A. AlShehri

1 paper indexed here

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Review Sep 2026

Biophysical and molecular mechanisms of lysosomal mechanoresilience: Membrane tension, TMEM63A, and cellular injury.

Lysosomal membrane failure contributes to cellular injury by disrupting degradation, metabolism, immune signaling, and compartmental integrity, yet the physical principles that determine whether a mechanically loaded lysosome adapts or ruptures remain incompletely resolved. This review integrates biophysical and molecu...

R. S. Hamad, A. El-kott, Sally Negm et al. · 0 citations

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