Author

Mohammad Umar

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Review Open access Sep 2026

Natural Bioactive Compounds in Rheumatoid Arthritis: Experimental Evidence from Adjuvant Arthritis Model Supporting Combination Strategies with Methotrexate

Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease that represents continuous synovial inflammation, oxidative stress, immune dysregulation, and progressive cartilage degradation and bone erosion. Although disease-modifying antirheumatic drugs (DMARDs), including methotrexate (MTX), have improved cl...

Mohammad Umar, Waqar Ahmad, K. Bauerová · International Journal of Mol... · 0 citations

Review Open access Jul 2026

Advanced CRISPR-Cas Genome Engineering Coupled with Nanotechnology-Based Drug Delivery for Treating Genetic and Infectious Diseases

Background CRISPR-Cas genome editing offers curative potential for monogenic disorders and persistent infections, but its clinical translation is hindered by delivery inefficiency, off-target effects, and immunogenicity. Nanocarrier platforms address these barriers by enabling targeted, transient intracellular delivery...

A. Aslam, F. Naz, Syeda Fatima Nadeem et al. · International Journal of Dru... · 0 citations