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Author

Mohammad Jawaıd Akhtar

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Aug 2026

Design, Synthesis, and Molecular Docking Studies of Coumarin-chalcone Conjugates as Selective TNF-α and Weak COX-2 Inhibitors with Efficacy as an Antioxidant.

It is suggested that coumarin-chalcone derivatives may act as a lead for the synthesis of more potent antioxidants and anti-inflammatory compounds.

Dalaa Ali El-Jadayel, Husna Khalifa Al-Busaidi, Zainab Hamood Al-Balushi et al. · 0 citations
Review Aug 2026

Unlocking the pharmacological potential of rhodanine derivatives: Drug design strategies and structure-activity relationships

Rational design strategies for rhodanine-based heterocycles and their therapeutic potential as antibacterial, anti-diabetes, anti-Alzheimer’s, anticancer, anthelmintic, anti-obesity, and against COVID-19 are discussed.

R. Nath, Lakshminarayan Das, Arka Chakraborty et al. · 0 citations
Review Open access Sep 2026

Rational drug design, synthetic and artificial intelligence approaches for bioactive heterocycles: advances and perspectives.

This review covers advances in designing and synthesizing bioactive heterocycles, highlighting structure-based drug design (SBDD) and ligand-based drug design (LBDD) approaches with computational modeling and Artificial Intelligence (AI) to find potent, selective molecules with good Absorption, Distribution, Metabolism...

Debajit Dewan, Bhupender Nehra, R. Nath et al. · 0 citations

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