Background Type 2 diabetes mellitus (T2DM) remains a major global health burden. Although glucagon-like peptide-1 receptor agonists (GLP-1RAs) such as dulaglutide improve glycemic control and promote weight loss, many patients do not achieve optimal metabolic targets. Mazdutide, a dual GLP-1 and glucagon receptor agoni...
Ahmad Hassan, Qurrat Ul Ain Farooq, Fnu Parwesh et al.· F1000Research· 0 citations
Cardiovascular-kidney-metabolic (CKM) syndrome describes the overlapping burden of metabolic dysfunction, chronic kidney disease, and cardiovascular disease. Tirzepatide and semaglutide are both recommended for patients with type 2 diabetes and obesity, yet no randomized trial has directly compared their effect on...
A. Qadeer, M. Khalid, D. Leblanc et al.· Clinical Medicine Insights:...· 0 citations
Background Left atrial appendage occlusion (LAAO) offers a mechanical alternative to anticoagulation for stroke prevention in nonvalvular atrial fibrillation patients. However, the optimal anesthetic strategy—general anesthesia (GA) versus conscious sedation (CS)—during LAAO remains unclear. Methods A systematic sear...
Abubakar Nazir, Ahmad Hassan, Maaz Amir et al.· F1000Research· 0 citations
LCC- and HF-related mortality declined overall, with descriptive subgroup variation by sex, race/ethnicity, urbanization, and geography, and targeted screening, hepatitis management, and equitable healthcare access are needed to address these patterns.
S. Khan, Muneeb Khawar, Muhammad Haris Khan et al.· ASIDE Gastroenterology· 0 citations
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