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Author

Mohamed Lotfy

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Open access Oct 2026

Metformin modulates survival, oxidative stress, and gene expression in a high-sucrose Drosophila diabetes model

Background Excess dietary sugar is a major contributor to metabolic disorders, including type 2 diabetes mellitus (T2DM). This study investigates the physiological, biochemical, behavioral, and molecular effects of high-sucrose diets in Drosophila melanogaster and evaluates the modulatory effects of metformin under the...

Mohamed Lotfy, Fatema Al Sawai, Dhoha Alyammahi et al. · 0 citations

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