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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Mirong Hou

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Open access Aug 2026

Acetoacetate–GPR43 axis epigenetically silences IL-6/CSF1 to restrict TAMs-driven metastatic lung cancer

A previously unappreciated collapse of acetoacetate homeostasis in lung cancer is uncovered, driven by the coordinated suppression of ketogenesis and increased ketolysis, resulting in a systemic acetoacetate deficiency.

Shuying Yuan, Biying Xiao, Shuai-Shuai Ni et al. · 0 citations

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