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Open access Aug 2026

DGAT1 regulates macrophage pyroptosis during Klebsiella pneumoniae infection

Klebsiella pneumoniae (Kp) is a Gram-negative opportunistic pathogen that causes severe infections, including pneumonia and sepsis, yet the molecular mechanisms governing macrophage cell death during Kp infection are incompletely understood. Here, we identify diacylglycerol acyltransferase-1 (DGAT1) as a critical...

Hui-Jung Jung, S. Jeong, Sang-Hee Lee et al. · 0 citations
Sep 2026

Appropriate Therapy and Survival in Carbapenem-Resistant Enterobacterales Bacteremia: A Multicenter Cohort Study on Epidemiology and Risk Factors.

BACKGROUND Carbapenem-resistant Enterobacterales (CRE) bloodstream infections are associated with high mortality and limited treatment options. This study aimed to characterize CRE epidemiology, identify risk factors for 30-day mortality, and evaluate the impact of appropriate combination therapy on mortality in patien...

Yae Jee Baek, Se Yoon Park, Jung Ho Kim et al. · 0 citations

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