Open access
Sep 2026
NDE1-Mediated Regulation of Neural Progenitor Regional Identity and Its Implication in Microcephaly
Using human brain organoids and mouse models, it is shown that loss of NDE1, a gene closely associated with microcephaly, disrupts progenitor identity, prolongs mitosis, and alters regional patterning in the forebrain.
R. Y. Tshuva, Jeyoon Bok, Mio Nonaka et al.
· Nature Communications · 0 citations