Open access
Sep 2026
Indole-AhR signaling shapes emotional regulation.
Wang et al. identify a gut-brain pathway in which loss of the commensal bacterium Alistipes shahii reduces indole production, prevents hippocampal indole-AhR signaling, and drives anxiety and depression behaviors in patients and mouse models of irritable bowel syndrome.1.
Minjeong Kim, H. Vuong
· Cell Reports · 0 citations