Molecules and Cells
Seokjun G. Ha, Minho Park, Jinwook Lee et al.
· 0 citations
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Open access
Sep 2026
Dual-targeted nanoparticles enable the ex vivo generation of cytotoxic and phagocytic CAR effector cells
Chimeric antigen receptor (CAR)-T cells and CAR-macrophages (or CAR-monocytes) offer complementary antitumor functions. CAR-T cells exert potent cytotoxicity against cancer cells, whereas CAR-macrophages can infiltrate solid tumors, phagocytose cancer cells and promote antigen spreading. Antibody-conjugated lipid nanop...
Ji-Su Hong, Jinwoong Lim, Minho Park et al.
· bioRxiv · 0 citations
Open access
Aug 2026
Focused framework sampling recovers binding-positive humanized anti-amyloid-β antibodies in a single sorting round
This workflow provides a practical route from immune-repertoire discovery to binding-positive humanized antibodies and applied the workflow to antibodies against amyloid-β (Aβ)-derived preparations.
Youngju Kim, Hayoung Kwon, Ji-Min Song et al.
· bioRxiv · 0 citations