Open access
Aug 2026
The KAT2/HDACⅡa-PGK-ALDO axis constitutes a dual degradation inhibition cascade links energy stress to glycolytic amplification.
A metazoan-conserved dual degradation inhibition cascade whereby energy stress coordinates acetylation-phosphorylation crosstalk that simultaneously enhances glycolytic output and suppresses two protein degradation systems is reported.
Chao-Gang Wang, Mingyang Du, Yutong Liu et al.
· Proceedings of the National... · 0 citations