A Multi-Epitope FimH-CsgA-OmpA-Based Vaccine Induces Broad Anti-Adhesion Activity and Protects Chickens Against Avian Pathogenic Escherichia coli O2 Challenge
Avian pathogenic Escherichia coli (APEC) causes substantial economic losses in the poultry industry, and vaccines capable of providing protection across diverse APEC strains remain needed. In this study, a FimH-CsgA-OmpA multiepitope fusion antigen (MEFA) was constructed and evaluated for immunogenicity, in vitro anti-...