Explainable Multiparametric MRI Radiomics Reveals Prognostically Relevant Intratumoral Heterogeneity in Rectal Cancer.
RATIONALE AND OBJECTIVES Clinically relevant intratumoral heterogeneity (ITH) in rectal cancer remains difficult to quantify noninvasively using conventional visual assessment of pretreatment magnetic resonance imaging (MRI). We developed an explainable multiparametric MRI radiomics signature for ITH-based risk stratif...