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Author

Mingdong Xu

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Aug 2026

Proton Sponge-Enabled Dual-Driven Nanomotors for MRI-Guided Tumor-Penetrating Synergistic Therapy of Pancreatic Cancer.

Dense stromal barriers and lysosomal sequestration severely restrict the extracellular transport and intracellular trafficking of nanomedicines in pancreatic cancer, while the robust glutathione (GSH)-dependent antioxidant defense further compromises therapeutic efficacy. Here, we developed a proton sponge-enabled dual...

Shuai He, Fulin Li, Pan Yang et al. · 0 citations
Open access Jul 2026

MRI-enabled ferroptosis self-amplifying nanoplatform synergizes with photothermal therapy to enhance chemotherapeutic efficacy against pancreatic cancer

This study presents a synergistic nanotherapeutic strategy that integrates chemotherapy, photothermal therapy, and ferroptosis-related mechanisms to overcome chemoresistance in pancreatic cancer.

Pan Yang, Shuai He, Mingdong Xu et al. · 0 citations

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