Traditional cancer treatment methods, such as chemotherapy, radiotherapy, and immunotherapy, are often limited by poor treatment efficacy, poor targeting, and adverse side effects, as well as intrinsic or acquired drug resistance, which are mainly caused by the complex and immunosuppressive tumor microenvironment. The...
This study overcomes the intrinsic trade-off between radiative and non-radiative decay pathways in aggregation-induced emission luminogens (AIEgens) for phototheranostic applications and enables effective imaging-guided eradication of MRSA in back and joint abscess models.
Qi-Cheng Zhang, Jian Zhang, Lei Ye et al.· Acta Biomaterialia· 0 citations
In mouse, rabbit, and non-human primate models with MPXV-induced skin damage, this hydrogel nanoparticle protective layer significantly inhibits viral replication and accelerates wound healing, representing a transformative, convertible platform for treating MPXV and other highly inflammatory viral infections.
Ning Shi, Xinyu Cao, Xiaolong Zhu et al.· Biomaterials· 1 citation
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