Open access
Sep 2026
Spatial and single-cell dissection of medulloblastoma identifies developmental hierarchies and a prognostic PPIA-BSG tumor-immune axis
Single-cell transcriptomic analysis delineates the cellular ecosystem of tumor and adjacent tissue-derived populations in MB, with particular emphasis on candidate cells of origin across molecular subgroups, and identifies PPIA-BSG co-receptor as a potential therapeutic target.
Ming-Ze Chen, Bai-Lin Duan, Jiao Zhang et al.
· Journal of Translational Med... · 0 citations