Ming-Yu Zhao

Integrative network toxicology, molecular docking, and in vitro experiments identify SLC6A2 as a novel candidate target in nicotine-induced osteoporosis.

In recent years, the health problems attributable to cigarette smoke (CS) have attracted widespread attention. However, the pathogenic mechanisms underlying osteoporosis development induced by nicotine, a neuroactive component of CS, remain unclear. In this study, we examined a potential molecular mechanism underlying...