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Aug 2026

Reprogramming Adenosine-Driven Tumor Immunosuppression With a Carrier-Free Nanoplatform for Self-Amplifying Antitumor Immunity.

Tumor microenvironment (TME) is a metabolically dynamic niche where dysregulated purinergic signaling plays a pivotal role in shaping antitumor immunity. Although immunogenic cell death (ICD) induces the release of extracellular ATP (eATP) to initiate immune activation, the overexpression of ectonucleotidases rapidly d...

Ming Yang, Zhichu Xiang, Mengyao Zhao et al. · 0 citations

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