Efficient Production of 14-Membered Macrolides by the Endophytic Fungus Colletotrichum gloeosporioides GLL-7 and Their Insecticidal Activity against Diaphorina citri.
Bioactivity-guided fractionation of the fungus Colletotrichum gloeosporioides GLL-7 yielded two macrolides: Sch725674 and Gliomasolide H (GLH), a novel macrolide that possibly targets phospholipid metabolism, disrupting lipid homeostasis and wax formation and is a promising lead compound for controlling D. citri, and C...