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Ming-Peng Shi

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Review Open access Oct 2026

Context‐dependent TREM2 signalling in myeloid cells: Molecular mechanisms and immunotherapeutic divergence in neurodegeneration and cancer

Abstract Background Triggering receptor expressed on myeloid cells 2 (TREM2) is a pivotal lipid‐sensing receptor that governs the functional plasticity and metabolic fitness of mononuclear phagocytes, including microglia, osteoclasts, dendritic cells and tissue‐resident macrophages. While originally identified as a gen...

Ya-Qing Lv, Ming-Peng Shi, Yong-Fei Zhao et al. · 0 citations

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