Dual Metabolic Inhibition Via Vanadium-NO Synergistic Nanoplatform Potentiates Cancer Immunotherapy.
Immunotherapy has emerged as a pivotal strategy in cancer treatment. However, tumor metabolic reprogramming not only promotes cancer cell survival but also fosters an immunosuppressive tumor microenvironment (TME), thereby hindering immune activation. To address these challenges, we developed a novel multifunctional hy...