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Author

Ming-Lun Li

2 papers indexed here

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Sep 2026

Molecular Programming of Steric Tags for Controlled Nanopore Translocation toward Precision Clinical Diagnostic Assistance

The precise resolution of single-molecule events is often limited by the stochastic thermal motion of analytes, which traverse nanoscale sensing zones too rapidly for conventional detection bandwidths. This remains a fundamental challenge in nanopore chemistry, particularly for small and flexible peptides. Here, we r...

Yi-Heng Liu, Shi-Jun Lin, Ming-Lun Li et al. · 0 citations
Oct 2026

Thermodynamic landscapes of conformational regulation during intrinsically disordered protein fibrillation.

Amyloid fibrillation of intrinsically disordered proteins (IDPs) involves a disorder-to-order transition driven by complex sequence-dependent interactions. However, how amino acid sequences and conformational ordering reshape the multi-chain free-energy landscape during fibril formation remains poorly understood. Here,...

Rui-Jun Gao, Ming-Lun Li · 0 citations

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