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Author

Ming-Fei Wu

2 papers indexed here

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Sep 2026

Photochemical Synthesis of 1-Propyl-3-phenylquinoxalin-2(1 H )-one: An Undergraduate Laboratory Experiment

3-Arylquinoxaline-2(1H)-ones are significant scaffolds in medicinal chemistry due to their diverse biological and pharmacological activities, such as neuroprotective and anti-cancer activities. While photo-induced synthesis has emerged as a sustainable approach to these compounds, existing protocols often require exp...

You-Lu Pan, Jun Li, Zun-Yuan Wang et al. · 0 citations
Sep 2026

Discovery of a Potent, Selective, and Orally Efficacious STAT6 PROTAC for the Treatment of Atopic Dermatitis

Signal transducer and activator of transcription 6 (STAT6), a key mediator of IL-4/IL-13 signaling, regulates Th2 differentiation, making it an attractive target for atopic dermatitis (AD). The reported phosphopeptide-based STAT6 proteolysis-targeting chimera (PROTAC) established proof of concept for targeted STAT6 d...

Wen-Tao Wang, Meng-Yu Zhao, Liu-Zhi Hu et al. · 0 citations

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